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QPS is a global
GLP-compliant contract laboratory supporting drug discovery and
development. Since 1995, we have provided high quality services
to pharmaceutical and biotechnology clients worldwide. We provide
industry-experienced scientists to manage your studies utilizing
the latest technologies and state-of-the art instruments. Our
four areas of expertise include:
►Bioanalysis
[LC/MS/MS, ELISA, Hybridization-ELISA]
►Drug
Metabolism and Pharmacokinetics (DMPK)
►Biomarkers (Protein/Biochemical
markers, Genomic
markers)
►Early clinical research
QPS-US LC/MS/MS
bioanalysis services are supported by 33 tandem mass spectrometers
including 25 Sciex API-4000's. QPS-Taiwan has 4 LC/MS/MS instruments
for GLP studies. The QPS large molecule quantitation team offers
ELISA and hybridization-ELISA for quantitative analysis of protein
drugs, oligonucleotide-based drugs, immunogenicity testing, and
cell-based assays.
QPS's IND-enabling
ADME (Absorption, Distribution,
Metabolism, and Excretion) package includes pharmacokinetics,
protein binding, tissue distribution by Quantitation Whole-Body
Autoradiography (QWBA) and microautoradiography, CYP450
and mass balance/excretion studies. We offer a full range of drug
metabolism capabilities including metabolic stability, inhibition
and ex vivo induction, reaction phenotyping, and metabolite profiling
and identification.
QPS-US also
provides rodent pharmacokinetics, protein binding, metabolic stability,
and in vitro CYP450 inhibition as part of our discovery screen.
QPS-Taiwan provides discovery dog pharmacokinetic studies.
The QPS biomarker
team offers both full GLP compliant and CLIA type ELISA approaches
to protein and biochemical marker analysis. Our molecular biology/genomic
services include RNA/DNA isolation, SNP genotyping and genetic
mutation analysis, quantitative RT-PCR, RNA expression analysis,
and microarray gene expression profiling.
QPS's early
phase clinical facility, Bio-Kinetic Clinical Applications,
has
over 240 beds and in the past 14 years has completed over 400
clinical trials involving nearly 11,000 study volunteers.
QPS-US Bioanalysis,
DMPK, Biomarker, and AAALAC-accredited
animal facilities are located in Newark, DE. The QPS-Taiwan facility
is located in Taipei, Taiwan. Bio-Kinetic Clinical Application
is headquartered in Springfield, MO.
No matter where in the world you are, QPS quality, service,
and turnaround are within your reach.
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