|
|
|
PHARMACOKINETICS
|
|
QPS scientists
and laboratory personnel are experts in designing, performing,
and interpreting the results of pharmacokinetic studies. The
laboratories
include an Association for Assessment and Accreditation of Laboratory
Animal Care (AAALAC) accredited rodent animal facility opened
in 2002 and state-of-the-art LC/MS/MS and immunoassay bioanalytical
equipment. QPS performs pharmacokinetic studies
for projects at the drug discovery stage (rapid turnaround), IND-enabling
studies, as well as toxicokinetic and clinical pharmacokinetic
studies.
Study design
and model selection are customized to meet specific project needs.
If required, pharmacokinetic study samples may include blood,
bile, cerebrospinal fluid or other matrices, as well as tissue
or tumor specimens that have special bioanalytical requirements.
LC/MS/MS
instruments typically perform the analysis of pharmacokinetic
samples, but specific studies may also employ immunoassays. Dosing
routes might examine nasal, intra-duodenal and intra-portal delivery
in addition to typical intravenous and oral routes.
Non-rodent
studies are performed through QPS partner laboratories in USA.
Discovery pharmacokinetic studies in dogs can also be conducted
in Taiwan with the study management and pharmacokinetic data analysis
performed in QPS-US.
|
|
|
©
QPS, L.L.C. . All rights reserved.
Drug Discovery - Drug Development - Site Map
3 Innovation Way, Suite 240 Newark, DE USA 19711 ph 302-369-5601
|