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Chairman,
President and CEO
Ben founded QPS in 1995. QPS has DMPK laboratories in Newark,
Delaware, clinical phase 1 unit in Springfield, Missouri, clinical/bioanalytical
labs in Taipei, Taiwan and sales office in many states of US.
Under his guidance; QPS is recognized as a premier Contract Research
Organization. QPS received Philadelphia 100 Award of 2005 - An
award organized by Wharton SBDC and its selection was based on
the top fast growing 100 companies in the tri-state area during
2002-2004. Dr. Benjamin Chien obtained his Ph.D. in analytical
chemistry (mass spectrometry) from the University of Michigan
at Ann Arbor with Prof. David M. Lubman. Ben is the co-inventor
of a novel Ion Trap/Time-of-Flight Mass Spectrometer. Ben began
his pharmaceutical career at DuPont Merck Pharmaceutical Co. in
the Drug Metabolism and Pharmacokinetics Section, where he built
the LC/MS/MS group dedicated to supporting drug discovery, preclinical
and clinical studies. In 1996, Ben received the Summit Award,
the highest level of achievement at DuPont Merck for his dedicated
contribution to the development of Efavirenz, an anti-viral drug
approved by the FDA for the treatment of HIV disease.
Chief Financial Officer
T. Ben Hsu, PhD, MBA, joined QPS in 2003 as Vice President, Finance
and Control and was promoted to CFO in 2005. Ben was with Aventis
Behring, a division of Aventis S.A., from 1999 to 2003 and was
Director of Global Finance Administration. Prior to joining Aventis,
he was with Lyondell Chemical Company (previously ARCO Chemical
Company) where he held posts in a variety of functions including
R&D, licensing, finance, and planning and control. Ben received
his BS degree from National Taiwan University and his Masters
and PhD degrees from the University of Delaware, all in chemical
engineering. He also earned an MBA in general administration and
finance from Drexel University.
VP of Operations
Kumar Ramu, PhD, joined QPS in 2000 as Vice President of Operations.
He previously served as a Group Leader at CoCensys and Purdue
Pharma, in the discovery, preclinical, and clinical drug development
departments of DMPK, as well as in toxicology and pharmaceutical
sciences, where he was involved in ERC/IND/CTX filings and regulatory
meetings. Kumar received his PhD in medicinal chemistry from the
University of Mississippi and obtained his post-doctoral training
in toxicology from the University of Texas at Austin.
Vice President of Global DMPK
Shang-Ying Peter King, PhD, joined QPS in 2005 as Vice President
of Global DMPK. Peter has over 21 years of pharmaceutical industry
experience supporting discovery and development of new chemical
entities. Prior to joining QPS, Peter was the Director of Pre-Clinical
Pharmacokinetics, US DMPK with Aventis/Sanofi-Aventis Pharmaceuticals.
Before working at Aventis, Peter had management responsibilities
in clinical and preclinical pharmacokinetics at Wyeth-Ayerst Research,
at Cephalon, Inc.and at DuPont Pharmaceuticals. Peter obtained
his PhD in pharmaceutics from the State University of New York
at Buffalo.
Senior Director
of Discovery and Preclinical Development
Helen Shen, PhD, joined QPS in 2002 as Director of Discovery
and Preclinical Development and was promoted to Senior Director
of
Discovery and Preclinical Development in 2005. Prior to joining
QPS, Helen held the position of Principal Research Scientist
at
DuPont Pharmaceuticals where she led a number of ADME teams and
was responsible for conducting DMPK activities for ERC/IND filing
as well as other non-clinical activities for IND. Helen received
her PhD in pharmaceutical chemistry from the University of California
at San Francisco and her post-doctoral training in pharmaceutics
from the University of Washington.
Principal
Clinical Pharmacokineticist of Global Clinical PK/PD Thomas
C. Chou, PhD, joined QPS in 2008 as a Principal Clinical Pharmacokineticist
of Global
Clinical PK/PD. Thomas has over 10 years of pharmaceutical
industry experience supporting clinical pharmacology and
development of
new chemical entities. Prior to joining QPS, Thomas was
a Senior Scientist in Clinical Pharmacology and Drug Dynamics with
Forest
Research Institute where he designed and conducted clinical
studies to examine ADME, drug-drug interaction, BA/BE and
pharmacokinetics properties in healthy subjects and special populations.
He
was
also responsible for performing pharmacokinetics (PK),
pharmacodynamics (PD), PK/PD correlation, population PK, and population
PK/PD
analyses as well as clinical trial simulations. Before
working at Forest, he served as a Clinical Pharmacokinetic Post-doctoral
Fellow at Janssen Research Foundation and a Clinical Pharmacokinetic
Intern at Wyeth-Ayerst Research. Dr. Chou obtained his
Ph.D.
in Pharmaceutics from University of Iowa.
Director
of Autoradiography
Eric Solon, PhD, joined QPS in 2002 as Director of Autoradiography.
Prior to joining QPS, Eric served as a Senior Scientist at DuPont
Pharmaceuticals, where he coordinated DMPK activities for ERC/IND
filings and implemented both macro- and micro-autoradiography
techniques to support drug discovery and development. Before joining
DuPont, he held various scientific posts at Ciba-Geigy Pharmaceuticals,
Novartis, and Schering-Plough Research Institute. Eric received
his PhD in Molecular Biology/Pathology from Rutgers University.
Eric is currently the President-Elect and Secretary of the Society
for Whole-body Autoradiography.
Director of
Discovery and Preclinical Development
Bruce Aungst, PhD, joined QPS in 2004 as Associated Director of
Discovery and Preclinical Development and was promoted to Director
of Discovery and Preclinical Development in 2006. His responsibilities
include the design of experiments, creating study protocols, managing
lab resources and projects, creating study reports, and enabling
clients to fulfill their discovery and preclinical ADME and pharmacokinetics
project needs. In previous positions at DuPont Pharmaceuticals
and Bristol Myers Squibb, he managed multidisciplinary ADME/Biopharmaceutics
teams. His work has led to the identification and discovery of
formulations for improving oral absorption and bioavailability.
Bruce obtained his PhD in pharmaceutics from the State University
of New York at Buffalo.
Associate
Director of in vitro and in vivo Metabolism
Ronghua Wang, PhD, joined QPS in 2005 as Associate Director of
in vitro and in vivo Metabolism. Prior to joining QPS, he was
a senior scientist at Vertex Pharmaceuticals and Millennium Pharmaceuticals
responsible for the metabolism of drug discovery and development
projects. He has extensive experience in structure elucidation
of metabolites of drugs and drug candidates using mass spectrometry
and NMR spectrometry. Ronghua received his PhD in pharmaceutical
sciences from the University of Rhode Island.
Research
Scientist
Foster P. Brown joined QPS in February 2003 as a Research Scientist.
As a Staff Scientist for DuPont Pharmaceuticals, Foster helped
create the first in-life animal research group within DuPont and
in 1992, became the supervisor of that group performing absorption,
distribution, metabolism and excretion studies (ADME) on various
animal models.
Animal Research
and Facility Manager
Brad Willis, DVM, joined QPS in August of 2002 as the Attending
Veterinarian and Supervisor of Animal Resources. Prior to joining
QPS, he was a Research Associate and Laboratory Manager for the
Department of Emergency Medicine at the Louisiana State University
Health Sciences Center in Shreveport. He has jointly published
several papers primarily involving ischemia/reperfusion studies
and activation of leukocytes and their effects on vascular [primarily
pulmonary] endothelium in rodents. Brad also served as Consultant
Veterinarian to and IACUC Chairman for Fabgennix, Inc. Brad received
his DVM from Kansas State University.
Lab Manager
of Autoradiography
Alfred Lordi, MS, joined QPS in 2002 as the Manager of Autoradiography.
Prior to joining QPS, Alfred worked in the toxicology departments
of Bio-Dynamics, Exxon Biomedical, and Schering-Plough Research
Institute where he coordinated DMPK study activities in whole-body
autoradioluminography (WBA), microautoradiography, tissue distribution,
and human radio-excretion studies. Alfred received his BS in animal
science from Rutgers University and his MS in biology from Seton
Hall University. Alfred is currently the Secretary of the Society
for Whole-Body Autoradiography.
Research Scientist
in Autoradiography
Nina S. Rebmann, BA, joined QPS in 2005 as a Research Scientist
in the Autoradiography laboratory. Prior to joining QPS, Nina
served as the lead scientist in whole-body autoradiography and
was instrumental in establishing the WBA capability for Aventis/Sanofi
Aventis US. She was also a member of the Global QWBA Integration
Team. Prior to Aventis, Nina was the lead scientist for WBA at
Novartis Pharmaceuticals and was a member of the Global PCS Network
for WBA. She has also worked at Princeton University in the Department
of Psychology and at Wyeth-Ayerst Research in the cardiovascular
department. She received her BA in biology at Douglass College
(Rutgers University). Nina is currently the Treasurer of the Society
for Whole-Body Autoradiography (US).
Senior Director of Operations
Yuen-Shek Chen, PhD, joined QPS in 1998 as Senior Bioanalytical
Scientist. He is currently serving as Senior Director of Operations
where he is responsible for all bioanalytical activities. During
his tenure with QPS, Yuen-Shek has been responsible for setting
up a dedicated DMPK bioanalytical unit and is also instrumental
in setting up the QPS-Taiwan operations. Yuen-Shek received his
PhD in organic chemistry from the University of Michigan at Ann
Arbor and his post-doctoral training from the University of Illinois
at Urbana-Champaign.
Director of
Bioanalytical Research
Yongdong Zhu, PhD, joined QPS in 1999 as Research Scientist and
was promoted to Director of Bioanalytical Research in 2003. Prior
to joining QPS, Yongdong held various scientific positions in
Yanshan Petrochemical Corporation including Senior Research Chemist
and Group Leader. Yongdong received his PhD in analytical chemistry
from the University of Michigan at Ann Arbor.
Head of Analytical
Research
Jamie J. Zhao, PhD, joined QPS in 2006 as Head of Analytical Research.
Prior to joining QPS, Jamie was a Senior Research Fellow at Merck
Research Laboratories and a Senior Research Scientist at Advanced
Bioanalytical Services, Inc. (now Advion BioSciences). Jamie has
authored approximately 25 peer-review journal publications and
over 50 scientific meeting presentations/abstracts in the areas
of mass spectrometry, bioanalytical, and pharmacokinetics. Jamie
received his PhD in analytical chemistry from the University of
Michigan at Ann Arbor and his post-doctoral training from Purdue
University.
Director
of Translational Medicine
Hui Zhang, MD, joined QPS in 2002 with extensive research experience
in hepatology/hematology, neuroscience and cancer at Materia Medica,
Mt. Sanai Medical Center, Cornell University Medical College,
and DuPont Pharmaceuticals. Since joining QPS, Hui has been involved
in the Immunoanalytical/ Biomarker area operational setup and
assay development. She is currently Associate Director in the
Immunoanalytical group.
QA Manager, Head of US QA Department
Wendy Finan, BS, joined QPS in April 2002 as a Senior Quality
Assurance Auditor and was promoted to QPS Quality Assurance Manager
(US) in September 2007. Wendy began her career at DuPont Pharmaceuticals
in 1989 in Drug Metabolism and Pharmacokinetics, and since then,
she has attained over 18 years of pharmaceutical industry experience
supporting discovery, method development, GCP, and GLP tox studies.
Executive Director of Strategic Planning and Marketing
Zamas Lam, PhD, joined QPS in 2000 as Account Manager and is currently
serving as the Senior Director of Specialized Client Development.
Prior to joining QPS, Zamas held various scientific and business
positions at the DuPont Corporation. Zamas received his PhD in
chemistry from the University of British Columbia and his post-doctoral
training from Harvard University.
Senior Director of Business Development
Jerry Gromelski joined QPS in 2002 as Director of Business Development
and was promoted to Senior Director of Business Development in
2007. A classically trained pharmacologist, he is currently responsible
for client services in the southeast region of the United States.
Prior to joining QPS, Jerry has 27 years of experience in the
CRO industry holding technical, operational, and business development
positions.
Executive Director & Head of Business Development
Livia Legg, MS, joined QPS in 2002 as Director of Business Development
and was promoted to Executive Director & Head of Business
Development in 2007 and is responsible for all Business Development
Activities. Livia started her career in business development at
Merck Pharmaceutical Co. and subsequently worked for an independent
laboratory in the areas of Drug Discovery and Preclinical Development.
She earned her MS degree from the University of New Hampshire.
Senior Director of Business Development
Robert P. Kokka, DrPH, joined QPS in 2003 as Director of Business
Development and was promoted to Senior Director of Business Development
in 2007. He is presently responsible for client services in the
western regions of the United States. Prior to joining QPS, Robert
served as Director of Scientific Affairs and Technical Services
for Roche Molecular Systems (Hoffmann-La Roche) and Bayer/Chiron
Nucleic Acid Diagnostics. Robert earned his BS degree from the
University of California, Davis and a DrPH in biomedical laboratory
sciences from the University of California at Berkeley.
Director of Business Development
Lily Rosa, MS, joined QPS in 2006 as Director of Business Development.
She is presently responsible for client services in the Midwest
and MA regions of the United States. Prior to joining QPS, Lily
has had business development and technical responsibilities at
various organizations including Ambion, Affymetrix, Procter & Gamble
Pharmaceuticals, and Cincinnati Children's Hospital. She earned
her MS degree from Iowa State University.
Vice President of Translational Medicine
LingSing K. Chen, PhD, joined QPS in 2005 as Executive Director
of Molecular Biology and is currently serving as the Vice President
of Translational Medicine. Prior to joining QPS, LingSing held
various positions at Wyeth Pharmaceuticals including Associate
Director
of Molecular and Cell Biology, Head of Ion Channel Molecular
Biology,
and Head of Wyeth-PanLabs natural product screening collaboration.
LingSing has served as senior advisor to Industrial Technology
Research Institute (ITRI) in Taiwan since 1999 where she also
helped establish the Biomedical Engineering Center to foster
the
growth of the biotechnology industry in Taiwan. Dr. Chen received
her MA and PhD in molecular biology from Princeton University
and her BS in biology from National Taiwan University.
Consulting Director
Check Y. Quon, PhD, MBA, joined QPS as Consulting Director in
2004. Prior to joining QPS, he was the Executive Director of Drug
Metabolism and Pharmacokinetics at DuPont Pharmaceuticals Co.
where he was responsible for the preclinical and clinical drug
metabolism and pharmacokinetics of all new chemical entities in
the cancer, cardiovascular, HIV, neurology, and inflammatory diseases
therapeutic areas. Check and his team have successfully filed
and gained approval of eight NDA's and one MAA, submitted over
50 IND's and 15 CTX's, and supported the nomination of over 100
drug candidates. Check has published more than 50 peer-reviewed
manuscripts, more than 80 abstracts and three book chapters in
the areas of preclinical and clinical drug metabolism, toxicokinetics,
preclinical and clinical pharmacokinetics and pharmacodynamics,
clinical pharmacology, and cardiovascular pharmacology. Check
received his PhD in pharmacology from the University of California
at Los Angeles and his post-doctoral training in oncology at the
McArdle Laboratory for Cancer Research at the University of Wisconsin.
He also earned an MBA from the University of Delaware.
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